Agios Pharmaceuticals, Inc. (AGIO) · Nov 5, 2026 · Earnings

Agios earnings beat as AQVESME grows, FDA decision slips

Beat — Revenue $55.4M vs ~$51.6M consensus; EPS $(1.09) vs $(1.24) consensus

Agios earnings show AQVESME gaining traction and revenue ahead of estimates, though the FDA decision for sickle-cell mitapivat is delayed.

Agios is transitioning from a development-stage biotech into a commercial rare-hematology company: AQVESME is its first major U.S. launch, while mitapivat approval in sickle cell disease is the larger next growth opportunity. The commercial launch was already showing momentum before this report, and the FDA’s three-month review extension was disclosed on October 30, so the quarter’s financial execution is newer information than the regulatory headline.

The quarter beat the published benchmark on both revenue and adjusted earnings expectations. Product revenue was $55.4 million versus a published consensus of roughly $51.6 million, while reported loss per share of $1.09 was better than the approximately $1.24 expected. The absolute revenue base is still small, but the launch is scaling rapidly from $12.9 million a year earlier.

	Q3 2026	Q3 2025	Consensus
Product revenue (Financial Statements)	$55.4M (+330%)	$12.9M	$51.6M
Net loss per share (Financial Statements)	$(1.09)	$(1.78)	$(1.24)
R&D expense (Financial Statements)	$73.5M (-15%)	$86.8M
SG&A expense (Financial Statements)	$56.5M (+37%)	$41.3M
Cash and marketable securities (Balance Sheet)	$907.0M (-22%)	$1.164B

AQVESME’s early commercial traction is the clearest business-positive signal. Agios added 177 completed U.S. start forms during the quarter, taking the cumulative total to 619, while approximately 75% of patients remained on therapy after six months. That supports the company’s claim that demand is broadening beyond an initial launch cohort, although prescriptions and persistence are not the same as recognized revenue or a full-year sales outlook.

The biggest offset is that the sickle-cell launch window moved later and now carries an explicit REMS question. The FDA extended the PDUFA date from November 1, 2026, to February 1, 2027, after requesting information on whether a risk-management program is necessary. That delay was already public before this 8-K, so it is not a fresh earnings surprise, but it keeps Agios from converting its largest indication opportunity into a near-term commercial catalyst.

Cost control is improving, but the company is still spending heavily to support the launch. R&D declined as programs moved through development and the operating model was resized, while SG&A rose because Agios is building commercial infrastructure for AQVESME and preparing for a potential sickle-cell launch. Cash remains substantial, but it fell from $1.16 billion at year-end to $907 million after nine months, leaving the 2028 profitability target dependent on continued product growth and disciplined spending.

Bottom line: This was a modestly better-than-expected commercial quarter, with AQVESME giving Agios real launch traction. The read is only slightly positive because the more important sickle-cell approval remains delayed and the regulatory review now includes a potential REMS question, though that issue was already known before the earnings filing.

What to watch next

FDA decision on mitapivat for sickle cell disease, February 1, 2027

Original filing on SEC EDGAR

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AllSight · BlackBerry Q2 FY27

Revenue $163.3M vs ~$144M expected; adjusted basic EPS $0.07 vs ~$0.04 consensus — a real upside surprise.Income statement
QNX revenue +27% to $80.3M; segment EBITDA $29.0M from $20.5M. “Record performance… core automotive.”Segment — QNX
Licensing jumped to $22.1M from $6.6M — it amplified the beat, but it's less recurring than QNX, so the quality sits in QNX.Segment — Licensing
FY27 guide lifted to $616–636M rev / $141–158M EBITDA, above the prior $594–621M / $119–139M framework.Guidance
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Events/ANDE/8-K · Earnings

8-K · Item 2.02 · Earnings

The Andersons — a record Renewables quarter that beat profit expectations

Filed Aug 3, 2026ANDE · NASDAQ

AllSight readBeatPriced in▲ 1.8% since filed · reaction agrees

adj. EPS $2.15 vs ~$1.48 consensus

This filing tests whether The Andersons' sharp profit increase reflects broad operating improvement or a one-off renewable-fuels boost. It also separates strong adjusted earnings and cash generation from the quarter's legal and impairment charges.

The quarter was substantially stronger than both last year and the published earnings expectation. Adjusted EPS reached $2.15, versus $0.24 a year earlier and above the published consensus of about $1.48; reported EPS was $1.65. Adjusted EBITDA more than doubled to $140 million, while sales slipped modestly — the improvement came from margins and operating performance rather than higher revenue. Financial Highlights · Statements of Operations

Q2 ($M, exc. per-share)	Q2 2026	Q2 2025	YoY
Sales & merchandising revenue	3,097.7	3,135.9	−1%
Net income (attributable)	56.6	7.9	+48.7
Diluted EPS	1.65	0.23	+1.42
Adjusted EPS	2.15	0.24	+1.91
Adjusted EBITDA	140.3	65.2	+75.1
Agribusiness adj. pretax	20.3	16.8	+3.5
Renewables adj. pretax	88.4	9.6	+78.8
Cash from operations	487.9	299.3	+188.6
Cash from ops (pre-WC)	112.9	42.9	+70.1

Renewables drove nearly all of the upside — the operating backdrop was strong, but the result also benefited materially from tax credits. Renewables' adjusted pretax income rose to $88 million on record production, stronger ethanol margins and merchandising gains. It also received $24 million of 45Z producer tax credits, so this was not solely a repeatable plant-margin improvement; the company did cite healthy export and domestic ethanol demand as supportive. Renewables — Record Q2 · Segment Data

Agribusiness improved, but it was a supporting contributor rather than the main earnings engine. Adjusted pretax income increased to $20 million as fertilizer margins improved and merchandising benefited from commodity-price volatility, despite lower fertilizer volumes. Agribusiness — Improved Q2 · Segment Data

Cash generation improved and funding capacity is comfortable, while reported earnings still absorbed meaningful non-core costs. Operating cash flow was $488 million ($113 million before working-capital changes); capital spending was $76 million. Adjusted EPS excludes $0.50 of legal-settlement, impairment and transaction items, so the $2.15 adjusted result runs ahead of the $1.65 reported. Leverage stays below the <2.5× debt-to-EBITDA target; no new quantified full-year outlook was given. Cash & Liquidity · Adjusted Net Income

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Agios earnings beat as AQVESME grows, FDA decision slips

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