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Companies · DNLI · Biological Products, (No Diagnostic Substances)

Denali Therapeutics Inc. (DNLI)

Denali Therapeutics Inc. (DNLI) stock — the fundamentals (P/E, market cap, valuation) and every material event, decoded in plain English.

Denali Therapeutics Inc. (DNLI) stock — financials & valuation

Key numbers for Denali Therapeutics Inc. (DNLI): P/E ratio, market cap, profit margins, returns, and whether the stock looks cheap or expensive versus its own 5-year range.

AllSight quality score: 34/100 — a percentile rank of Denali Therapeutics Inc.’s fundamentals against Manufacturing peers, weakest on growth. A quality ranking, not a price prediction.

Market cap$3.3B
P / S910.6×
EV / EBITDA-5.8×
Gross margin97.4%
Operating margin-15058.2%
Net margin-14191.2%
Return on equity-61.4%
ROIC-84.9%
Debt / equity0.0×
Dividend yield0.0%

Is Denali Therapeutics Inc. overvalued? P/S looks overvalued vs its 5-year range; P/B looks fair vs its 5-year range.

Independent of the events above — derived from Denali Therapeutics Inc.’s own financial statements and shown as context, never as advice.

Aug 6, 2026
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